Home Chemistry Heterocyclic Building Blocks Pyridines Oxazolo[5,4-B]Pyridine
Electrophilic Aromatic Substitution: The pyridine ring in oxazolo[5,4-b]pyridine can undergo electrophilic aromatic substitution reactions, where an electrophilic reagent adds to the aromatic ring. For example, you can perform reactions like nitration, halogenation, or Friedel-Crafts acylation/alkylation.
Nucleophilic Substitution: If there are suitable leaving groups, you can carry out nucleophilic substitution reactions. For instance, you can perform SN1 or SN2 reactions on the oxazolo[5,4-b]pyridine ring.
Ring-Opening Reactions: The oxazole ring can be susceptible to ring-opening reactions under specific conditions. This might involve nucleophilic or electrophilic attack on the oxazole ring.
Heterocycle Formation: Oxazolo[5,4-b]pyridine can participate in various heterocyclic synthesis reactions, where it reacts with other compounds to form new heterocycles.
Reduction: Reduction reactions can be carried out to reduce the nitrogen or oxygen atoms in the ring system, depending on the reaction conditions and reagents used.
Cross-Coupling Reactions: You can perform cross-coupling reactions using suitable reagents and catalysts to introduce different substituents onto the oxazolo[5,4-b]pyridine ring.
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6-Bromo-2-(trifluoromethyl)oxazolo[5,4-b]pyridine
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